Mason has held a variety of positions at Spurs, including two spells as interim boss, since he returned to the club in 2018.
The once-capped England midfielder was forced to retire from playing at the age of 26 following a fracture to his skull in a game for Hull at Chelsea in 2017.
He started his coaching career at boyhood club Tottenham months after his retirement before he was asked to take charge of the first team in 2021 following the departure of Jose Mourinho.
Mason subsequently led Spurs in their 1-0 defeat to Manchester City in the Carabao Cup final at Wembley.
Antonio Conte promoted Mason to his coaching staff upon his appointment and the 33-year-old had another interim spell towards the end of the 2022-23 campaign.
Having worked under current Tottenham boss Ange Postecoglou for the last 16 months, Mason has held talks with Anderlecht over their vacant head coach position and could now be set for his first managerial role.
Ryan Mason enjoyed two spells in interim charge of Spurs (John Walton/PA)