Tottenham will be looking to start the Europa League knockout phase in style when they face AZ Alkmaar on Thursday night. Paired against the Dutch side when the draw was made in February, Ange Postecoglou's team will play away from home first before crucially having home advantage in the second leg next Thursday.
Tottenham are the current favourites to lift the Europa League trophy in Bilbao come May but AZ will be intent on throwing a spanner in the works. Maarten Martens' side should certainly not be underestimated after hitting Galatasaray for four in their home encounter against the Turkish team last month.
Whereas AZ were in action on Sunday as they lost 3-1 at Heerenveen, Spurs went without a game following their FA Cup fourth round exit at the hands of Aston Villa. Postecoglou is likely to tinker with his side from last Wednesday's defeat at home to Manchester City and there is the possibility that some of his returning players feature in Alkmaar.
But what changes could take place? football.london takes a look below.
Cristian Romero/Micky van de Ven for Archie Gray
We may well see a change in defence from last week as Cristian Romero and Micky van de Ven are now back in Tottenham training. The return of the duo is huge for Postecoglou after going without his first-choice centre-back pairing for quite some time.
The Australian is unlikely to throw both players in at the deep end, with Romero maybe the one ahead of his teammate right now as he returned to training last week. If there is indeed to be a change, Archie Gray may be the one who drops out of the team.
Romero was seen partnering Kevin Danso in Tottenham training and that could be Postecoglou's selection choice in the Netherlands.
Djed Spence for Destiny Udogie
Djed Spence was a big miss for Tottenham last Wednesday up until he entered the field in the closing stages of the 1-0 defeat. Now available for Europa League action after making the 25-man squad this time around following his omission for the league phase, the 24-year-old looks to be in a good position to return to the side.
As Pedro Porro was given a breather at Ipswich Town just over a week ago, Destiny Udogie may be the player to drop out of the side this time to accommodate Spence. That means the ex-Middlesbrough player would operate at left-back but he is more than accustomed to the role now going on the amount of football he has played there under Postecoglou.
Pape Matar Sarr for Lucas Bergvall
Lucas Bergvall now appears to be one of Postecoglou's first-choice midfielders after wowing in his game time since December. The 19-year-old and Rodrigo Bentancur take up two of the three midfield berths in the Tottenham team, with James Maddison or Dejan Kulusevski, who is now out through injury, usually completing the preferred triumvirate.
One potential option for Postecoglou in midfield is Pape Matar Sarr after a really strong campaign to date in the Europa League from the Senegalese star. If Sarr comes in then Bergvall may be the player at risk.
Dominic Solanke/Son Heung-min for Mathys Tel
Postecoglou may elect to switch things up in attack after Mathys Tel's struggles against Manchester City last Wednesday. However, the Europa League may be the ideal competition for the Frenchman right now as he looks to fully adapt to the Tottenham team.
If Tel does drop down to the bench in Alkmaar, Dominic Solanke or Son Heung-min could possibly lead the line. A start for Solanke may come too soon upon his return from injury and minutes from the bench may be more likely to begin with.
Son Heung-min for Brennan Johnson/Wilson Odobert
Son dropped down to the bench against Manchester City eight days ago and Postecoglou's selection decision proved to be a talking point before and after the game. The Spurs captain looks set to come back into the side and regain his place on the left-wing.
Wilson Odobert impressed there in Tottenham's previous game and he could have done enough to keep his place in the side. The summer signing does offer Spurs versatility and that could see him switch over to the right in order for Son to play in his natural role.
Postecoglou may want to keep Brennan Johnson in the XI, though, considering his goalscoring form this campaign, thus possibly seeing Odobert subsequently take his place on the bench.
Click here to listen to the latest episode of Gold & Guest Talk Tottenham.