Rangers have been paired with seventh-place Olympiakos and will face either Bodo/Glimt or Fenerbahce in the last 16.
Bodo/Glimt beat Twente in a thrilling play-off tie, losing the first leg 2-1 but won the second 5-2 after extra-time.
Fenerbahce drew 2-2 at Anderlecht last night but won the first leg 3-0 to secure safe passage.
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Manchester United and Tottenham are paired after finishing the league phase in third and fourth, meaning they will be on different sides of the draw.
It also meant that both Premier League clubs will have had a keen eye on the same play-off matches last night.
In those ties, AZ Alkmaar beat Galatasaray 6-3 on aggregate, while Real Sociedad knocked out Midtjylland by a 7-3 aggregate scoreline.
AZ are on the left side of the bracket with fellow play-off winners Viktoria Plzen, Bodo/Glimt and Ajax.
La Real are on the right with AS Roma, Fenerbahce and FCSB.
Good afternoon everyone, and welcome to Express Sport's live coverage of the Europa League draw.
Manchester United, Tottenham Hotspur and Rangers are set to learn their last-16 opponents and routes to the Bilbao final on May 21.
Stay tuned for regular updates across the next couple of hours...