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The last-eight tie, our reward for convincing victories over Barnsley and Leicester City in the competition, will take place on Thursday 19 December.
Kick-off at the Tottenham Hotspur Stadium is 20:00 GMT and the match is being shown live on Sky Sports Main Event.
The other three matches are being played a day earlier, with staggered start times.
Arsenal and Crystal Palace compete in a London derby, Newcastle United host Brentford and Liverpool are away at Southampton.
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