Recent form
Spurs have won just one of their last seven Premier League matches, defeating Southampton 3-1 near the start of the month.
Ange Postecoglou's side entered the weekend occupying 16th place in the standings on 37 points.
Their form in the Europa League is better, however, and they progressed to the semi-finals with a 2-1 aggregate victory over Eintracht Frankfurt last week.
This game precedes the first leg of their last-four tie with Norwegian outfit Bodo/Glimt.
Key players
Brennan Johnson has been Tottenham's main source of goals so far this season with 16 in all competitions.
Dominic Solanke has had spells out through injury and is second-best in the team on 12. James Maddison and captain Son Heung-min, who is sidelined through injury, have 11 apiece.
Son has the highest number of assists for Spurs in 2024-25 thus far on 11, with Dejan Kulusevski and Maddison one behind.
Team news
Tottenham have no fresh concerns within their squad following the defeat by Nottingham Forest last time out.
Son remains out with his foot problem and defender Radu Dragusin is recovering from surgery on an anterior cruciate ligament injury.
Previous meetings
This will be the clubs' fourth and final encounter of the campaign.
In the reverse Premier League fixture, Liverpool ran out 6-3 winners in the capital just before Christmas.
They would be paired together in the semi-finals of the Carabao Cup and after Spurs edged the first leg 1-0, the Reds scored four without reply in the return match at Anfield to book their Wembley spot.
What they said
Postecoglou, Tottenham head coach
"You want to go there and compete against a very good side and compete well. It's not about getting through unscathed, you want to get through having played well against a top team. Irrespective of what's on the horizon, that's still of primary importance to us.
"In the [Carabao Cup semi-final] first leg I thought we were really good. We took the game to them, even though we had quite a few absences, and worked really hard to get a win in that game. We know it's going to be tough on the weekend but, at the same time, I think it's a great chance for us."
Pre-match stats
Tottenham have won just two of their last 24 Premier League games against Liverpool, with both victories coming at home.
Spurs have failed to keep a clean sheet in any of their last 18 matches versus the Reds in the top flight.
None of Tottenham's last 15 league matches on the road have finished in a draw (won five, lost 10).
Richarlison has scored in four of his last five Premier League appearances and all four of the Brazilian's goals against Liverpool have been at Anfield.