Rangers will have to be at their best when they face Spurs with Philippe Clement hoping to maintain momentum and pull off a shock.
Ange Postecoglou has some injury problems to deal with, however, the Light Blues manager has a squad that is starting to look stronger ahead of what could be a big night at Ibrox.
With an even bigger game on Sunday against Celtic, this is who Clement has picked for Rangers to face Spurs.
Rangers team news vs Spurs confirmed
The one area of the park where the Gers boss likes to keep rotation to a minimum is in defence.
Leon Balogun has strolled through domestic games recently, but Robin Propper has saved his best performances for the Europa League.
Keeping Balogun fresh for the Premier Sports Cup final makes sense.
James Tavernier has made a timely return to form with Dujon Sterling pushing the Rangers captain for a place in the starting XI, any dip in form and Clement has an easy decision to make.
An easier decision seemed to be to go with the midfield that performed so well against Nice in the last Europa League league phase fixture, however, Clement has sprung a surprise.
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Nedim Bajrami gets a start as the main attacking midfielder with Mohamed Diomande alongside Nicolas Raskin.
Who starts up front for Rangers against Spurs?
Not having Ianis Hagi and Danilo available is a blow, but Rangers have coped without them so far.
With two goals and an assist against Nice, Hamza Igamane is the only option to lead the line.
His hold up play, and composure could be crucial in getting Rangers up the park where Vaclav Cerny and Nedim Bajrami have the ability to make a difference.
On the left, Ridvan Yilmaz – where he has played off the bench recently – will provide pace and energy and, hopefully, play his part on the counterattack.
The forward line will have to be more clinical than it has been at any point this season if Rangers are to get a result against the team Chris Sutton branded “the best in the Premier League”.
Line-up: Butland, Tavernier, Jefte, Propper, Balogun, Raskin, Diomande, Bajrami, Cerny, Ridvan, Igamane