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The defender came on for Micky van de Ven at half-time in Thursday’s 3-0 win over Elfsborg, which secured Spurs a spot in the Europa League top eight.
However, Dragusin was forced to leave the pitch just 20 minutes later after an awkward landing on his knee, and he is currently being assessed.
Although Postecoglou is still uncertain about the extent of the injury, Dragusin will not be part of the squad for this weekend’s game.
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