Eintracht Frankfurt will have twice as many players than Tottenham absent for their Europa League quarter-final first leg on Thursday evening.
Spurs have been hampered by injuries this season but Ange Postecoglou has finally seen those concerns lessen with Cristian Romero, Wilson Odobert and Richarlison all currently available after a challenging last few months for the trio.
Destiny Udogie and Micky van de Ven have also endured injury-riddled campaigns with both defenders left on the bench for Sunday's 3-1 Premier League win over Southampton at Tottenham Hotspur Stadium
"Yeah Destiny and Micky are fine. They have missed a lot of football this year so it made sense to put them on ice today," explained Postecoglou this past weekend.
On Wednesday, he added: "Most of our guys now are in a position where they are not fatigued because they haven’t been overplayed but they have played enough and that has been really important for us. So we are in a good position from that point of view."
Richarlison returned to the matchday squad for the visit of the Saints but three players are still missing. Radu Dragusin has already been ruled out for the season while Dejan Kulusevski and Kevin Danso are dealing with minor issues that will keep the duo out of both legs.
"Kevin and Deki are working hard still," Postecoglou admitted earlier this month when asked about their respective hamstring and foot issues. "They’re probably a couple of weeks away, but both are progressing well."
As for Frankfurt, Dino Topppmoller looks set to be without some key players including striker Elye Wahi, the replacement for Omar Marmoush, and Ansgar Knauff. The latter was pushing to return but he has since been confirmed out for the first leg.
"Unfortunately, Ansgar Knauff isn’t quite ready," Topppmoller said on Wednesday.
"We’ve got a few ideas about how to replace him. We’ll find a solution-oriented option and play in a system that’s well-suited to the opposition.”
The 23-year-old is a key player for Frankfurt in attack having picked up three assists from his last four starts with two of those coming in the last-16 6-2 aggregate triumph over Ajax.
Can Uzun, Eric Ebimbe, Krisztian Lisztes, Timothy Chandler and experienced goalkeeper Kevin Trapp all missed the weekend defeat to Werder Bremen and it does not look as though any will return on Thursday.
Sinking Saints and preparing for Frankfurt, click here to listen to the latest episode of Gold & Guest Talk Tottenham