Our no.7, who celebrated her 25th birthday last month, has been selected in the starting XI for the clash with Spurs at Leigh Sports Village (kick-off 12:30 BST).
It means Tooney will become the first outfield player to appear in 93 consecutive WSL games for the same club, according to Opta.
The England international overtakes the previous record of 92, held by Kerys Harrop for Birmingham City.
The overall record, when you add goalkeepers into the equation, is kept by former Reds stopper Mary Earps with 102 appearances.
Ella starts her third successive league match for Marc Skinner’s side this season. She played the full 90 in our opening 3-0 win against West Ham at Old Trafford and 76 minutes in the 1-0 victory at Everton that followed, before sitting out the 2-0 League Cup success over Liverpool at Leigh in our last outing - a game Marc Skinner and the rest of the squad dedicated to her father, Nick, who recently passed away at the age of 59.
Along with Millie Turner and Leah Galton, Ella is one of the only remaining members from our 2018/19 title-winning inaugural squad.
Joining United at the age of eight, the attacking midfielder has established herself as one of the pioneers of women’s football at her childhood club and paved the way for many young girls in the sport.
Tooney told us recently that she accepts growing responsibility as a long-serving player, on the back of an impressive 2023/24 season.
During the campaign, Ella surpassed the 50-goal mark for the Reds, won four Player of the Month prizes, and claimed our Women’s Goal of the Season award for her stunning FA Cup final strike against today’s opponents Tottenham.
Congratulations on breaking another record, Tooney!
Listen to radio commentary of United Women v Tottenham Hotspur on ManUtd.com and in the United App from 12:30 BST.