Ndombele joined from Lyon in 2019 with huge expectations after shattering Tottenham's transfer record.
But he would go on to play just 91 times for the club, scoring 10 goals and is now set to leave one year before the end of his contract.
Richarlison almost broke the £50m mark when he arrived from Everton in 2022 as Harry Kane's back-up.
And while his tally of 12 goals this season was a significant increase on the three from his opening Spurs campaign, he is being linked with a departure this summer.
Johnson was signed by Ange Postecoglou last summer and has impressed in patches during his first season in North London.
He scored five goals and 10 assists in 38 games and will look to build on that in the 2024/25 campaign.
Romero initially joined on loan from Atalanta in 2021, before his impressive displays saw him secure a permanent deal the following year.
He is two games shy of 100 for Spurs and, while he can be reckless with his tackling at times, is beginning to form a promising partnership with Micky van de Ven.
Maddison was handed Kane's No10 shirt after arriving at Spurs and hit the ground running with three goals and five assists in his opening 11 matches.
But after getting injured against Chelsea in October, he failed to return with the same sharpness - managing just five goal contributions in 15 league matches as he missed out on England's final 26-man squad for the Euros.
Sanchez joined Spurs from Ajax in 2017 and played more than 200 games across a six-year spell.
But he was always considered a somewhat erratic defender who did not play more than 20 games in a Premier League season from 2020 onwards.
Porro was another signing who originally arrived on loan in January 2023, before he signed permanently last summer.
He has 54 appearances for Spurs under his belt, scoring seven goals and impressing under Postecoglou this season.
Rapid Dutch centre-back Van de Ven was named Spurs Player of the Season in his first campaign at the club.
His pace, athleticism, and technical ability on the ball have made him arguably Postecoglou's best signing to date.
Sissoko came to North London for a substantial fee after being relegated with Newcastle and went on to enjoy five years at Tottenham, playing more than 200 games.
Unfortunately for the French midfielder, he is best-known for giving away a controversial penalty for handball in the first minute of Spurs' 2-0 Champions League final defeat to Liverpool in 2019.
Lo Celso joined on loan from Real Betis in 2019 - a deal that was made permanent the following season.
He has 10 goals and eight assists in 108 games, with some Spurs fans still unsure about the Argentine.