Tottenham have endured some mixed fortunes in the Premier League this season, but their Europa League record is as yet unblemished.
Spurs have picked up two wins from two in Europe this season, seeing off Qarabag at home before a hard-fought win away at Hungarian side Ferencvaros.
Now their attention turns to Dutch outfit AZ Alkmaar, who have won one and lost one so far in the Europa League.
The Sporting News looks at the latest team news and predicted lineups for this game at the Tottenham Hotspur Stadium.
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Tottenham vs. AZ Alkmaar lineups, predicted starting 11, team news
Given Spurs' hectic schedule, Ange Postecoglou could use this game as an opportunity to rotate his side, although he's limited to an extent with fringe stars Wilson Odobert and Djed Spence both out injured.
Radu Dragusin should get a chance in central defence, while it could be the ideal time for Richarlison to start after a long time out with injury. Youngsters Archie Gray and Mikey Moore could also be given game-time – depending how heavily Postecoglou wants to rotate his lineup.
Tottenham predicted lineup (4-3-2-1, right to left): Vicario (GK) — Gray, Dragusin, Romero, Davies — Sarr, Bentancur — Bergvall, Maddison, Werner — Richarlison
Injured: Oosterwolde, Under, Yuksek, Osayi-Samuel, Egribaya
Suspended: None
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Former Spurs youngster Troy Parrott returns to the club where he learned his trade, having left permanently in the summer after a series of loans. He should start up front.
AZ have Ibrahim Sadiq, Bruno Martins Indi, Mexx Merdink and Wouter Goes all out with injuries. Former Southampton midfielder Jordy Clasie should start for the visitors.
AZ Alkmaar predicted lineup (4-3-3, right to left): Owusu-Oduro (GK) — Maikuma, Penetra, Dekker, Wolfe — Clasie, Mijnans, Koopmeiners — Buurmeester, Parrott, Van Bommel
Injured: Sadiq, Martins Indi, Merdink, Goes
Suspended: None
Tottenham vs. AZ Alkmaar live stream, TV channel
Here's how to watch this Champions League match across selected areas of the world's major regions: