The Hammers make two changes to the starting eleven since their last Premier League outing against Nottingham Forest, with Nuno finally opting for a top two.
Thomas Frank makes three changes to the Tottenham side that lost 2-1 to Aston Villa in the FA Cup last weekend.
Conor Gallagher starts in midfield after completing his £35 million move from Atletico Madrid earlier this week, replacing Joao Palhinha.
Here is the Tottenham team that Thomas Frank has selected to face West Ham United in the Premier League on Saturday
Thomas Frank has made three changes to his Tottenham Hotspur team to face West Ham in Saturday's Premier League London derby.
We can now confirm our starting XI and substitutes for today's Premier League encounter against West Ham (kick-off 3pm).
Tottenham Hotspur CEO Vinai Venkatesham has admitted the men's team has "fallen short of where we want to be so far this season" and said the club "must add more quality, experience, and leadership to compete consistently at the highest level."
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Fixture: Tottenham Hotspur vs West Ham United
Competition: Premier League
Kick-off: 15:00 UK time
